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Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission

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文献出处
Science China(Life Sciences)  2020年03期
机 构
Key,Laboratory,of,Molecular,Virology,and,Immunology,Institut,Pasteur,of,Shanghai,Center,for,Biosafety,Mega-Science,Chinese,Academy,of,Sciences,Key,Laboratory,of,Synthetic,Biology,CAS,Center,for,Excellence,in,Molecular,Plant,Sciences,Chinese,Academy,of,Sciences,The,Joint,Program,in,Infection,and,Immunity:Guangzhou,Women,and,Children’s,Medical,Center,Guangzhou,Medical,University,The,Joint,Program,in,Infection,and,Immunity:Institute,Pasteur,of,Shanghai,Chinese,Academy,of,Sciences,Key,Laboratory,of,Systems,Biomedicine,Ministry,of,Education,Shanghai,Center,for,Systems,Biomedicine,Shanghai,Jiao,Tong,University,National,Engineering,Research,Center,for,the,Emergence,Drugs,Beijing,Institute,of,Pharmacology,and,Toxicology
基 金
supported,in,part,by,grants,from,the,National,Science,and,Technology,Major,Projects,for,“Major,New,Drugs,Innovation,and,Development”,(directed,by,Dr.,Song,Li),(2018ZX09711003),of,China,the,National,Key,R&D,Program,(2018YFC0310600),of,China,the,National,Natural,Science,Foundation,of,China,(31771412),Special,Fund,for,strategic,bio-resources,from,Chinese,Academy,of,Sciences,(ZSYS014)
论文摘要

Dear Editor,The occurrence of concentrated pneumonia cases in Wuhan city,Hubei province of China was first reported on December 30,2019 by the Wuhan Municipal Health Commission (WHO,2020).The pneumonia cases were found to be linked to a large seafood and animal market in Wuhan,and measures for sanitation and disinfection were taken swiftly by the local government agency.The Centers for Disease

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